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Clinical studies show people using topiramate alongside lifestyle changes lose approximately 5 to 7 percent of starting body weight during this window
Over 16 weeks, the median body weight dropped from 223 lbs (101 kg) to 203 lbs (92 kg)
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Medicare, through Part D, currently covers the medications only for patients with type 2 diabetes, obstructive sleep apnea, or noncirrhotic metabolic dysfunction-associated steatohepatitis
Pain 158 , 23402353 (2017)
This complication has been assessed with multiple systematic reviews with meta-analyses demonstrating that while there may be an increased risk of acute pancreatitis with the DPP-4 inhibitors, there is no clear association with GLP1-RAs 16
